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Open access Oct 2026

EPHA4 Regulates the Transition between Mesenchymal and Hybrid States in TNBC

Metastatic progression in triple-negative breast cancer (TNBC) is strongly influenced by epithelial-mesenchymal plasticity (EMP), which enables transitions between epithelial, hybrid epithelial/mesenchymal (E/M), and mesenchymal cell states. While mesenchymal cells are highly invasive and resistant to therapy, hybrid E...

Wen-Chao Liu, Hoi-Wan Lee, M. Bungert et al. · 0 citations
Open access Aug 2026

S9.3 - Non-canonical effects of non-reproductive factors on reproduction

The hypothalamic-pituitary-gonadal axis (HPG) controls pubertal development, sexual maturation, and fertility. We identified a role of hypothalamic microglia in controlling the HPG axis through Rank signaling. Whole-body and microglia Rank depletion led to hypogonadotropic hypogonadism (HH) resulting from an alterati...

E. Suarez · 0 citations

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