Author

E. Sulman

3 papers indexed here

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Nov 2026

Survival in patients with renal cell carcinoma and brain metastases: an update of the Renal Graded Prognostic Assessment.

BACKGROUND Brain metastases are a common and serious consequence for patients with renal cell carcinoma. This study aimed to determine if survival has changed since the introduction of current therapies, identify prognostic factors, update the prognostic index (the Renal Graded Prognostic Assessment [GPA]) in the conte...

P. Sperduto, F. Johri, Hany Soliman et al. · The Lancet Oncology · 0 citations

Open access Aug 2026

Persistent chromatin alterations and gene expression reprogramming follow widespread DNA damage in glioblastoma

DNA damage from routine cellular processes or exogenous insults can have a lasting impact on gene regulation beyond genetic mutations1, 2, 3, 4–5. The prevailing paradigm for the consequences of DNA damage repair revolves around restoration of the original genetic sequence, but long-term changes in chromatin configurat...

A. Modrek, K. Chandradoss, Catherine Do et al. · Nature Communications · 0 citations

Jun 2025

Persistent chromatin alterations and gene expression reprogramming follow widespread DNA damage in glioblastoma

DNA damage from routine cellular processes or exogenous insults can have a lasting impact on gene regulation beyond genetic mutations. The prevailing paradigm for the consequences of DNA damage repair revolves around restoration of the original genetic sequence, but long-term changes in chromatin configuration, gene ex...

A. Modrek, K. Chandradoss, Catherine Do et al. · bioRxiv · 0 citations