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Open access Sep 2026

612. Astrocyte-mediated inflammatory response as a promising target for TRP: a study in humanized Alzheimer’s disease mice model

Abstract Background Chronic inflammation within the central nervous system is a defining feature of many neurological and neurodegenerative disorders, including Alzheimer’s disease (AD). Astrocytes, the most abundant glial cell population in the brain, play a pivotal role in maintaining neuronal homeostasis, synaptic s...

A. Basta-Kaim, E. Trojan, K. Kamińska et al. · 0 citations
Open access Sep 2026

613. The analysis of the impact of non-steroidal drug and the TRP compound on the immune profile of microglia: study in an Alzheimer’s disease model

Abstract Background Neuroinflammation is a hallmark of central nervous system (CNS) disorders and plays a critical role in the progression of neurodegenerative diseases, including Alzheimer’s disease. Microglia, the resident immune cells of the CNS, act as key regulators of inflammatory responses and are rapidly activa...

E. Trojan, K. Kamińska, M. Leśkiewicz et al. · 0 citations

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