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Author

E.A. Tsarenkova

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Open access Oct 2026

Spatial Transcriptomic Profiling of FAP-Positive Cells in Gastric Cancer and Association with Immunotherapy Efficacy.

INTRODUCTION The spatial heterogeneity of the tumor microenvironment in gastric cancer, particularly in the stromal compartment, remains poorly characterized. Fibroblast activation protein (FAP)-positive cancer-associated fibroblasts (CAFs) are known to promote tumor progression, immune evasion, and therapeutic resista...

L. Tashireva, A. Kalinchuk, E. Shmakova et al. · 0 citations
Open access Oct 2026

Head-to-Head Comparison of FAP Antibody Clones for Tissue Expression Analysis

Background: Fibroblast activation protein (FAP) is a promising target for cancer diagnosis and therapy, but the specificity and sensitivity of anti-FAP antibodies used for immunohistochemistry (IHC) vary considerably. A head-to-head comparison of commercially available clones is needed to guide antibody selection, ther...

E. Shmakova, A. Kalinchuk, E. Tsarenkova et al. · 0 citations
Review Aug 2026

Predictors of immunotherapy response in gastric cancer: the role of the tumor microenvironment and integrative predictive models.

This review synthesizes current data on cellular, molecular, and systemic predictors, focusing on immune cell phenotypes, protein biomarkers, gene signatures, and metabolic factors, focusing on immune cell phenotypes, protein biomarkers, gene signatures, and metabolic factors.

E. Tsarenkova, A. Kalinchuk, E. Shmakova et al. · 0 citations

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