E. Tsiani

Hypoxia-Driven Extracellular Vesicle Signaling in Lung Cancer Progression, Immune Evasion, and Therapeutic Resistance

Tumor hypoxia is a defining feature of solid tumors, including lung cancer, and a major driver of aggressive disease progression, metastasis, and therapeutic resistance. Although hypoxia-induced signaling is well-characterized at the cellular level, emerging evidence highlights extracellular vesicles (EVs) as critical...