Open access
Aug 2026
Sirtuin signalling governs calcium homeostasis and mitochondrial function in metabolic syndrome cardiomyocytes
Abstract Metabolic syndrome (MetS) is a major contributor to cardiovascular disease and is characterized by impaired Ca2+ handling and mitochondrial dysfunction in cardiomyocytes. However, the upstream mechanisms linking metabolic stress to these alterations remain incompletely defined. Here, we investigated whether si...
F. Akat, Leila Aryan, Suatnur Şık et al.
· Experimental Physiology · 0 citations