Author

E. Vingolo

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Review Open access Aug 2026

Peripheral Exudative Hemorrhagic Chorioretinopathy: Current Concepts, Multimodal Imaging, Differential Diagnosis and Emerging Therapeutic Perspectives

Peripheral exudative hemorrhagic chorioretinopathy (PEHCR) is an uncommon but likely underrecognized degenerative retinal disorder characterized by peripheral subretinal and sub-retinal pigment epithelium hemorrhagic and exudative lesions, predominantly affecting elderly individuals. The condition frequently mimics cho...

Feliciana Menna, L. De Luca, Alessandro Meduri et al. · Journal of Clinical & Tr... · 0 citations

Review Open access Sep 2026

The Oxidative–Mitochondrial–Inflammatory Axis in Retinitis Pigmentosa: Extracellular mtDNA as Biomarker and Therapeutic Read-Out

Retinitis pigmentosa (RP) is the most common inherited retinal dystrophy (prevalence ~1:4000) and a leading Mendelian cause of working-age blindness. Despite marked genetic heterogeneity, its progression converges on a common secondary cascade of outer-retinal hyperoxia, increased reactive oxygen species (ROS), and mit...

Rossella Grimaldi, Francesca Franco, E. Vingolo · Antioxidants · 0 citations

Review Open access Sep 2026

Choriocapillaris Dysfunction in Retinal Diseases: Multimodal Imaging Biomarkers, Pathophysiological Insights, and Emerging Clinical Applications

The choriocapillaris is the terminal capillary bed that sustains the retinal pigment epithelium (RPE) and the outer retina, and its integrity is inseparable from that of the RPE–Bruch’s membrane complex it supplies. Histopathological work established decades ago that choriocapillaris density declines with age and falls...

Feliciana Menna, Alessandro Meduri, L. De Luca et al. · Biomedicines · 0 citations