Oleuropein Reduces Secondary Injury Pathways After Experimental Spinal Cord Injury Via HMGB1-Associated Signaling
Objective Spinal cord injury (SCI) can cause profound disability and substantial morbidity and mortality. Oleuropein (OLE) is a phenolic compound with anti-inflammatory and antioxidant effects. High mobility group box 1 (HMGB1), released extracellularly after tissue injury, can amplify inflammatory signaling. This stud...