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Author

Edward C. Holmes

3 papers indexed here

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Open access Sep 2026

A divergent betacoronavirus with a functional furin cleavage site in South American bats

Bats are natural reservoirs for a wide range of RNA viruses. Members of the genus Betacoronavirus, including Severe Acute Respiratory Syndrome virus 2 (SARS-CoV-2) and Middle East Respiratory Syndrome virus (MERS-CoV), have attracted particular attention due to their recent zoonotic emergence. However, much of the know...

Kosuke Takada, Nicholas Yamahoki, Jonathon C. O. Mifsud et al. · 0 citations
Open access Aug 2026

The RNA virome of early metazoans sheds light on long-term virus-host relationships

These findings expand the known diversity and host range of several virus groups, and shed light on virus evolution in early metazoans, demonstrating both host jumping within aquatic environments and virus host-associations that may span the entirety of animal evolution.

Ayda Susana Ortiz-Baez, Jonathon C. O. Mifsud, Jasper W. Schwarz et al. · 0 citations
Open access Aug 2026

Cryo-EM structure of piscine orthoreovirus reveals structural conservation across 450 million years of viral evolution

Structural modifications suggest that PRV uses mechanisms for entry and assembly that diverge from MRV, and advance the structural characterization of PRV and enhance the understanding of structural determinants of orthoreovirus cell and tissue tropism.

Kenta Okamoto, A. Munke, Gavin S. Treadaway et al. · 0 citations

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