Aug 2026
In silico and in vitro evaluation of new sulfonamide derivatives as VEGFR-2 inhibitors for cancer therapy.
The most promising compound was K4, which produced potent inhibition of VEGFR-2 and the highest selectivity index (SI) of all tested compounds and that K4 represents a potentially important candidate for continued preclinical development.
Ahmed Wheed Radhi, Hayder Ghanim Chfat, Zahraa Sabbar Omarn et al.
· Future Medicinal Chemistry · 0 citations