Microemulsion Eyedrop for Delivery of a PPARα Agonist To Improve Diabetic Keratopathy Corneal Wound Healing.
Diabetic keratopathy (DK) is characterized by delayed corneal wound healing in diabetes, and recent studies have linked this defect to impaired mitochondrial respiration and reduced peroxisome proliferator-activated receptor-α (PPARα) signaling in the corneal epithelium. The PPARα agonist fenofibrate (Feno) has shown t...