Berberine as a multi-hallmark modulator of aging: From AMPK and mitophagy to inflammaging and the SASP.
Berberine, a naturally occurring isoquinoline alkaloid found in several medicinal plants such as Berberis spp. and Coptis chinensis has long been used in traditional medicine. Recent evidence positions berberine as a pleiotropic modulator of multiple interconnected hallmarks of aging, making it a promising candidate fo...