Aug 2026
Precise dual-gene knockout of MSTN and SOCS2 via cytidine base editing enhances muscling and growth in goats
This study successfully established a YE1-AncBE4max-based platform for efficient, precise dual-gene editing in goats and showed that the edited goats exhibited significantly increased body weight and a "double-muscling" phenotype by 90 days of age compared to wild-type controls.
Ling Li, Ming-Xing Cao, Muhammad Farhab et al.
· Functional & Integrative Gen... · 0 citations