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Author

Elçin Bakır

2 papers indexed here

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Open access Sep 2026

EVALUATION OF THE HEPATOPROTECTIVE EFFECTS OF VITAMIN E AND ALPHA-LIPOIC ACID AGAINST DIMETHOATE TOXICITY IN VITRO

Objective: In this study, the protective effects of vitamin E (Vit E) and alpha-lipoic acid (LA) against the hepatotoxicity of dimethoate, a widely used organophosphate pesticide, were investigated.Material and Method: The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) test was applied to evaluate c...

Elçin Bakır, Burcu Ünlü Endirlik, Ayşe Eken · 0 citations
Sep 2026

Rational design of hybrid hydrazide-hydrazone/thiourea derivatives as potential VEGFR-2 targeting anticancer agents: synthesis, biological evaluation, and mechanistic insights into anticancer activity.

The development of novel anticancer agents capable of modulating pathways associated with tumor progression remains a critical strategy, particularly for aggressive breast cancer subtypes such as triple-negative breast cancer (TNBC). In this study, a new series of hydrazide-hydrazone/thiourea derivatives (MIH-31-46) wa...

Guzide Satir-Basaran, Ahmed Amleh, Antonio Curcio et al. · 0 citations

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