Predictive Modeling of Cognitive Decline in Alzheimer’s Disease via Multi-Modal Digital Twins: Algorithmic Limitations, Explainable AI, and Healthcare Management Perspectives
The heterogeneous progression of Alzheimer’s disease (AD) continuously challenges the boundaries of traditional clinical neurology, particularly in early diagnosis and the personalized administration of disease-modifying therapies. In recent years, the paradigm of the “digital twin” a dynamic, data-driven in silico rep...