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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

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Eleanor A. Degen

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Open access Aug 2026

A reaction-diffusion framework for de novo Polycomb spreading

Eukaryotic organisms rely on post-translational modifications to chromatin to maintain stable patterns of gene silencing. These modifications include trimethylation at histone H3 lysine 27 (H3K27me3), which is deposited by Polycomb Repressive Complex 2 (PRC2) and accumulates on the genome during embryogenesis. While th...

Eleanor A. Degen, Shelby A. Blythe · 0 citations
Open access Aug 2026

Nucleation-dependent propagation of Polycomb modifications emerges during the Drosophila maternal to zygotic transition

During zygotic genome activation in Drosophila, broad domains of Polycomb-modified chromatin are rapidly established across the genome. Here, we investigate the spatial and temporal dynamics by which Polycomb group (PcG) histone modifications, H3K27me3 and H2Aub, emerge during early embryogenesis. Using ChIP-seq and li...

Natalie Gonzaga-Saavedra, Eleanor A. Degen, Isabella V. Soluri et al. · 0 citations

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