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Author

Elena Perez

1 paper indexed here

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Nov 2026

Calreticulin exposure is a critical mediator of high-dose vitamin C-induced immune surveillance in the tumor microenvironment.

High-dose vitamin C (vitC) has shown superior anticancer activity in immunocompetent compared with immunodeficient mice, suggesting an immunodependent mechanism of action. Because high-dose vitC generates substantial reactive oxygen species (ROS), we hypothesized that ROS could induce immunogenic cell death (ICD), a re...

Alessandro Cavaliere, F. Maione, M. Macagno et al. · 0 citations

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