Author

Elena Vezzoli

1 paper indexed here

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Open access Jul 2026

Structure-function dissection of huntingtin exon 1 identifies a PRD-driven modifier of neuronal toxicity in Huntington’s disease

These findings highlight the PRD’s contribution to HD toxicity and point to MKL2/MRTFB and the cytoskeleton and transcriptional coactivator MKL2/MRTFB and the cytoskeleton as candidate mediators.

R. Iennaco, Camilla Maffezzini, Simone Maestri et al. · bioRxiv · 1 citation