Rethinking diabetic retinopathy: Homeostatic mechanisms for retinal clearance.
AIMS Diabetic retinopathy (DR) is a sight-threatening consequence of diabetes. DR disrupts cell-to-cell communication in the retinal neurovascular unit (NVU), impairing blood flow which leads to vascular complications. Here, we propose an integrated framework of DR pathogenesis in which impaired clearance mechanisms an...