Elham Zokaei

Pdcd4–Rictor interaction suppresses mTORC2-PFKFB3 axis and tumorigenesis in NSCLC

Programmed cell death 4 (Pdcd4) is a well-established tumor suppressor as well as an inhibitor of protein translation. Although Pdcd4-mediated translational repression contributes to tumor suppression, emerging evidence suggests that Pdcd4 also exerts translation-independent functions. In this study, we found that Pdcd...