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Author

Elif Çelik

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Open access Sep 2026

Transcriptomic Characterization of TCR-NK Cells Reveals Challenges Associated with CD3ζ Overexpression.

Objective TCR-engineered NK cells represent a promising strategy for targeting intracellular tumor antigens while overcoming the risk of TCR alpha/beta chain mispairing inherent to TCR-engineered T cells. Previous work showed that CD3ζ overexpression in TCR-NK cells did not improve antigen-specific cytotoxicity and ins...

Tolga Sütlü, Elif Çelik, Betül Çakici et al. · 0 citations

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