Renal Single-Nucleus Transcriptomic of a New Model of Cardiovascular-Kidney-Metabolic (CKM) Syndrome in Aging Swine
CKM syndrome entails pathophysiological interactions among the heart, the kidneys, and metabolic derangements. The specific cell populations implicated in renal injury have yet to be identified. We leveraged a new model of CKM syndrome in aging swine and single-nucleus RNA sequencing (snRNA-seq) to investigate the rena...