UTILIZING POLYETHYLENE GLYCOL TO IMPROVE THE SOLUBILITY AND DISSOLUTION RATE OF CLARITHROMYCIN BY THE SOLID DISPERSION METHOD
Clarithromycin (CAL), a poorly water-soluble agent, is a novel broad-spectrum macrolide antibiotic utilised in various infections. The current study aimed to enhance its solubility and dissolution rate by formulating solid dispersions with different polyethylene glycols (PEG). These solid dispersions were synthesised v...