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E. Schwarz

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Open access Aug 2026

Psychometric validation of research domain criteria, general health, and clinical-psychosocial parts of the minimum dataset of the German Center for Mental Health—informing a Delphi process

This study evaluated the latent structure and conceptual validity of the Research Domain Criteria (RDoC), General Health, and Clinical/Psychosocial clusters of the German Center for Mental Health (DZPG) Minimum Data Set (MDS). It aimed to determine whether these clusters represent interpretable constructs and demonstra...

Bernd R. Förstner, S. Böttger, Timm Seegert et al. · 0 citations
Open access Oct 2026

Real-world alcohol cue exposure and drinking risk in alcohol use disorder

Alcohol-related cues are thought to contribute to drinking in alcohol use disorder (AUD), but their contribution in daily life remains difficult to separate from changing social contexts and internal states. We used ecological momentary assessment in two independent cohorts of non-treatment-seeking individuals, compris...

A. Ghadami, Abhijit Sreepada, I. Reinhard et al. · 0 citations
Open access Sep 2026

Resting-state brain age is associated with cognitive and sensorimotor abnormalities in schizophrenia spectrum disorders: a validation & longitudinal study

Brain-age models use neuroimaging features to predict chronological age. The resulting brain-age gap (BAG), defined as predicted brain age minus chronological age, quantifies deviations from age-expected brain characteristics. Structural brain-age acceleration is well established in schizophrenia spectrum disorders (SS...

S. Volkmer, S. Fritze, D. Altinok et al. · 0 citations
Review Open access Jul 2026

Benchmarking large language models against practicing clinicians on psychopathological assessment

Psychiatry’s reliance on language makes LLMs a natural tool for psychopathological assessment, yet structured, item-level assessments from psychiatric clinical interviews remain under-researched. In this proof-of-concept study, 10 LLMs assessed transcripts of three simulated psychiatric interviews across all 100 items...

E. Lenz, J. Naamanka, Wolfgang Trabert et al. · 0 citations
Open access Jul 2026

Genome-wide association analyses of borderline personality disorder identify 11 loci and highlight shared risk with mental and somatic disorders

BPD showed the strongest positive genetic correlations with GWAS of post-traumatic stress disorder, depression, attention deficit hyperactivity disorder, antisocial behavior, antisocial behavior, and measures of suicide and self-harm.

F. Streit, S. Awasthi, Alisha S. M. Hall et al. · 1 citation

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