PARP inhibitors have become an integral component of treatment strategies for advanced epithelial ovarian cancer, particularly in
BRCA1/2
-mutated and homologous recombination-deficient (HRD) tumors. Despite clinically meaningful improvements in progression-free survival, a substantial proportion of patients develo...
D. Incognito, G. Ciappina, G. Ettore et al.· Frontiers in Oncology· 0 citations
Carnosinemia, also referred to as carnosinase 1 (CNDP1) deficiency, is an ultra-rare inborn error of metabolism characterized by impaired CNDP1 activity and carnosine degradation. The clinical significance and phenotypic spectrum of this condition remain poorly defined, with highly heterogeneous neurological and deve...
Giuseppe Carota, Alessio Ardizzone, L. Buccarello et al.· Orphanet Journal of Rare Dis...· 0 citations
Psoriasis is a chronic inflammatory skin disorder characterized by keratinocyte hyperproliferation, immune dysregulation, oxidative stress, and impaired epidermal barrier function. In the present study, we investigated the protective effects of Tempol, a membrane‐permeable nitroxide with antioxidant and anti‐inflammato...
S. Scuderi, M. Lanza, A. Capra et al.· Mediators of Inflammation· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
