Background: Accelerated vascular aging, assessed as artificial intelligence-based vascular age (AIVA), is associated with small vessel disease that may impact brain structure and neuropsychological function. Methods: In a cross-section of Framingham Heart Study participants, AIVA was estimated using a validated convolu...
Leroy L. Cooper, Ayantika Banerjee, A. Beiser et al.· Arteriosclerosis, Thrombosis...· 0 citations
Background Identifying candidate biomarkers for preclinical dementia could improve our understanding of underlying biological pathways leading to vascular brain injury (VBI) and neurodegeneration. Objective To identify plasma protein markers of MRI markers of VBI and amyloid- and tau-PET burden in cognitively healthy a...
Martin D. Mulligan, Rui-Qi Wang, Qiong Yang et al.· Journal of Alzheimer's Disea...· 0 citations
Higher DHRPS was associated with lower cognitive function in older adults beyond HR or steps alone, and longitudinal evaluation of DHRPS exposures is needed to determine its utility for predicting cognitive decline trajectories.
Jie He, Yuan-Kai Zhang, Xu-Zhi Wang et al.· Journal of the American Hear...· 0 citations
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