Crosstalk between protein kinases Pho85-Pho80 and Rim11 regulates Pah1 phosphatidate phosphatase function in lipid synthesis
In Saccharomyces cerevisiae, the Pah1 phosphatidate (PA) phosphatase is essential for the synthesis of the storage lipid triacylglycerol. Through its utilization of the substrate PA, Pah1 also exerts a negative regulatory effect on phospholipid synthesis, a process required for cell growth and proliferation. The functi...