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Author

Emily R. Sartori

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Open access Aug 2026

Cholesterol Dysregulation in APOE4 Astrocytes Promotes α-Synuclein Pathology in miBrains

An iPSC-based 3D model that integrates neurons, glia, myelin, and cerebrovascular cells into a human brain-like tissue (“miBrain”) is developed and establishes a robust model for investigating protein inclusions in human iPSC-derived brain tissue.

Louise A. Mesentier-Louro, Camille Goldman, Sebastian Gaese et al. · 2 citations
Open access Sep 2026

Large-scale single-molecule analysis of tau proteoforms

Iterative Mapping of proteoforms provides insights into proteoform complexity at the single-molecule level, with implications for understanding protein regulation in neurodegenerative diseases and beyond.

James Joly, V. Budamagunta, Zheng-Jian Zhang et al. · 1 citation

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