Abstract PR008: Oligodendrocyte-secreted factor L-PGDS potentiates phagocytosis of tumor-associated myeloid cells in pediatric high-grade gliomas
Pediatric brain tumors are the most common solid tumors in children. Pediatric high-grade gliomas (pHGGs) account for approximately 17% of brain tumors in children aged 0–14 years and remain largely incurable. Immunotherapies, including immune checkpoint blockade, have shown minimal benefit in pHGGs, largely due to i...