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Emma C. Jerome

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Open access Sep 2026

α2δ-2 mediates coupling of presynaptic calcium entry to vesicle release in hippocampal parvalbumin-expressing interneurons

The α2δ family of auxiliary voltage-gated calcium channel (VGCC) subunits have critical but incompletely understood roles in brain function. Parvalbumin-positive (PV+) interneurons in the hippocampus highly express the α2δ-2 isoform, and mice lacking α2δ-2 exhibit spontaneous seizures. Thus, we examined PV+ neuron-medi...

Allison J. Ellingson, Emma C. Jerome, Ashlynn A. Gallagher et al. · 0 citations

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