Jul 2026
Regulation of Neutrophil Heterogeneity and Effector Functions by the NLRP3 Inflammasome in Sepsis 2306743
It is found that Nlrp3 is not required for LDN/HDN recruitment in sepsis, however, the LDNs and HDNs from Nlrp3-deficient mice demonstrated reduced NETosis, and scRNA-Seq analysis revealed that neutrophil subtype clustering is altered in Nlrp3-/- mice during sepsis.
Duane Jeansonne, Emmanuelle M. L. Ruiz, J. Le et al.
· Journal of Immunology · 0 citations