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Author

Eneko Merino-Casamayor

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Open access Sep 2026

Astrocytic PI3Kα controls synaptic plasticity and cognitive function via serine metabolism

Astrocytes modulate neuronal activity by gliotransmission and through metabolic regulation, yet the relationship between these functions remains poorly understood. Here we show that phosphatidylinositol 3-kinase (PI3K) signaling in astrocytes controls synaptic plasticity and memory by regulating cellular metabolism. De...

Alba Fernández-Rodrigo, Celia García-Vilela, Abel Eraso-Pichot et al. · 0 citations

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