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Enrico Rossignolo

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Open access Aug 2026

When bigger is not better: the impact of RefSeq growth on Kraken2 classification accuracy

This study analyzed the influence of RefSeq database size and composition on taxonomic identification performance using Kraken 2, a widely used taxonomic classification and profiling method and found that resource-efficient Kraken 2 Lite (capped) databases generally exhibit lower classification accuracy compared to ful...

Leonardo Lazzaro, Enrico Rossignolo, Matteo Comin · 0 citations

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