Regulation of acute myocardial infarction by CircTMCC1 through mitochondrial dysfunction and AMPK/mTOR-driven M1 macrophage polarization: role in QFR assessment.
Assessment of circTMCC1 expression in human coronary artery segments, peripheral blood mononuclear cells from CAD patients, M1 macrophages, and an AMI mouse model suggests it may serve as a promising diagnostic biomarker and therapeutic target for CAD and AMI, potentially improving prognosis.