Multiple myeloma (MM) is the second most common hematological malignancy. Ferroptosis, a distinct form of programmed cell death, has attracted the interest of researchers because of its unique role and biological significance across various diseases. As a first-line clinical treatment drug for MM, lenalidomide (LEN) ha...
BACKGROUND
Triple-negative breast cancer (TNBC) is a clinically challenging disease subtype of breast cancer, with therapeutic outcomes remaining unsatisfactory due to its highly invasive potential. Ferroptosis, a newly identified type of programmed cell death, is mediated by the iron-dependent accumulation of lipid pe...
Xue Mao, Yin Lin, Zhifeng Gu et al.· Biochemical and Biophysical...· 0 citations
RSV is a potential therapeutic drug for ferroptosis-related AA treatment by targeting the PI3K/AKT/mTOR signaling pathway, which enhances NRF2-mediated GPX4 transcription, thereby ameliorating AA symptoms in vitro and in vivo.
Erhao Zhang, Jia-Nan Cui, Xinran Zhu et al.· Chinese Medicine· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.