Author

Éric Massé

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Aug 2026

Seed pairing between a small regulatory RNA and target mRNA determines cleavage by a RNase E with a minimal C-terminal scaffold.

Small regulatory RNAs (sRNAs) can specifically bind to their target mRNAs to inhibit their expression, either by promoting degradation or by blocking translation. However, the molecular determinants that select which repression mode an sRNA employs remain poorly understood. To investigate this, we used the model target...

Carlos Daniel Vega Valle, Karine Prévost, David Lalaouna et al. · RNA: A publication of the RN... · 0 citations

Open access Aug 2026

Peptidoglycan remodeling prevents antibiotic resistance during oxidative stress

The bacterial small RNA (sRNA) OxyS is expressed in Escherichia coli during oxidative stress. The sRNA OxyS enhances cell survival by controlling genes involved in the regulation of hydrogen peroxide (H2O2) and iron-sulfur (Fe-S) cluster formation. Here, we used the MS2 affinity purification coupled with RNA sequencing...

Jonathan Sukadi Miala, Léanne Arcand-Carrier, Rosalie Lapointe et al. · bioRxiv · 0 citations