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Author

Erica N. Larschan

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Review Open access Aug 2026

Before hormones: early sex-specific mechanisms shaping nervous system development, function, and postnatal disease susceptibility

Brain development requires precise spatiotemporal regulation of gene expression and molecular processes to establish healthy and functional neural circuits. Traditionally, sex differences in brain development have been attributed primarily to gonadal differentiation and the subsequent actions of sex hormones on develop...

Maria A. Tsiarli, Erica N. Larschan · 0 citations
Open access Aug 2026

The transcription factor CLAMP is required for neurogenesis in Drosophila melanogaster.

It is suggested that CLAMP regulates a core transcriptional program which drives NSC proliferation and differentiation via cell-intrinsic and niche-dependent mechanisms involving niche glia and transcriptional regulation of Notch and Tailless.

Maria A. Tsiarli, James A. Kentro, A. Conard et al. · 0 citations
Open access Aug 2026

Mapping genome-wide RNA-RNA and RNA-DNA interactions in nuclear hubs of male and female Drosophila cells

The sex-specific RNA-RNA interaction map within the nucleus is determined and the target loci of various RNA molecules, including small nuclear RNAs (snRNAs), which are core components of the spliceosome–a ribonucleoprotein complex involved in RNA splicing are pinpointed.

Sarah Gunasekera, Megan Carlson, Mukulika Ray et al. · 0 citations

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