Erick Bahena-Culhuac

Systematic benchmarking of AlphaFold and SWISS-MODEL kinase structures for structure-based drug discovery.

Accurate protein structure prediction is fundamental to structure-based drug discovery. However, the practical performance of deep learning-based models such as AlphaFold compared with traditional homology modeling approaches like SWISS-MODEL remains incompletely evaluated in realistic drug-design workflows. Here, we s...