Author

Erik A. Imel

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Review Open access Aug 2026

Burden of Disease in Pediatric Tumor-Induced Osteomalacia: A Literature Review

Tumor-induced osteomalacia (TIO) is an ultra-rare, paraneoplastic syndrome caused by tumors secreting fibroblast growth factor 23 (FGF23). In children, TIO may be mistaken for more common causes of rickets and osteomalacia, including monogenic forms, leading to long diagnostic delays. This review aimed to identify evid...

S. Minisola, Suzanne M. Jan de Beur, Thomas O. Carpenter et al. · Calcified Tissue Internation... · 0 citations

Open access Jul 2026

HR-pQCT measures of bone in autosomal dominant osteopetrosis highly correlate with fractures and inversely correlate with bone resorption markers

Overall, the data reveal the profound, yet variable, phenotype in ADO and indicate that HR-pQCT measures correlate with disease severity and represent potential surrogate endpoints for future therapeutic trials.

Stuart J. Warden, Erik A. Imel, Zi-Yue Liu et al. · Journal of Bone and Mineral... · 0 citations