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Erin D. Jeffery

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Open access Sep 2026

Sperm development requires TMC5-dependent mechanoresponsive calcium entry

Spermiogenesis, the transformation of round spermatids into streamlined, fertilization-competent sperm, represents cellular morphogenesis at its most extreme1,2. Despite decades of effort, spermiogenesis remains difficult to recapitulate outside the testis2,3, highlighting the importance of cues within the native tissu...

Wenhao Zheng, Lorena Roa-de la Cruz, John Duncan et al. · 0 citations

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