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Author

Erin E. Grundy

2 papers indexed here

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Sep 2026

Abstract B086: Mesothelin-targeted CAR Th1/17 cells are a novel cellular engineering platform for pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) remains refractory to immunotherapies, including adoptive T cell therapy, necessitating evaluation of alternative T cell engineering platforms in immunosuppressive solid tumors. Human CD4+ T cells co-secreting IFN-γ and IL-17A (Th1/17 hybrids) have demonstrated enhanced ant...

Delaney K. Geitgey, Megan M. Wyatt, Maggie J. Phillips et al. · 0 citations
Sep 2026

Abstract A026: Bulk deconvolution analysis identifies subtype-specific methylation differences in pancreatic cancer patients

While the two transcriptional subtypes (basal-like and classical) of pancreatic ductal adenocarcinoma (PDAC) offer an opportunity for precision medicine, current subtype-specific therapy options are limited to existing frontline therapies with poor outcomes. To determine whether there are epigenetically-driven di...

Erin E. Grundy, Margaret A. Hall, Y. Yoo et al. · 0 citations

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