Open access
Jul 2026
Mammalian-evolved strains of the fungal pathogen Cryptococcus neoformans show adaptation via heritable transcript level differences specific to mouse MHC haplotype.
BACKGROUND Organisms adapt to novel environments using changes to genome, gene expression, and protein functions. This study focused on changes that had occurred when a fungal pathogen previously encountered hosts that differed only at the major histocompatibility complex (MHC) region, loci that control immune recognit...
Carter B Ayers, Matt J. Nalley, H. Madhani et al.
· BMC Genomics · 0 citations