Open access
Sep 2026
A single-cell view of human tissue aging reveals architectural decline beyond cellular composition
Aging reshapes the human body at the cellular level, yet how cell identity, morphology, and spatial organization remodel across organs and the adult lifespan remains poorly mapped, at a scale and lifespan coverage that molecular spatial assays cannot yet reach. Treating the GTEx histopathology archive as a population-s...
Ernesto Abila, Yimin Zheng, Z. Bagó-Horváth et al.
· bioRxiv · 0 citations