Comparative Evaluation of Immunohistochemistry With DNA Methylation Profiling for Molecular Classification of Medulloblastomas: A Single-Institution Cohort Study.
Medulloblastoma is an embryonal tumor of the central nervous system that is divided into 3 molecular subgroups: WNT-activated, SHH-activated, and non-WNT/non-SHH-activated. The latter comprises group 3 and group 4. Given significant prognostic differences, distinguishing molecular subgroups is important. Although a pan...