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Author

Estere Seinkmane

2 papers indexed here

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Open access Oct 2026

The mTOR pathway drives daily physiology

How molecular clocks drive daily rhythms in mammalian physiology remains poorly understood. Here we show that the mechanistic target of rapamycin (mTOR) pathway is required for most daily variation in cellular and organismal physiology. PERIOD2 binds to mTORC1 and limits its activity, providing a route by which the clo...

Aiwei Zeng, A. Mihut, M. Anandapadamanaban et al. · 0 citations
Open access Jul 2026

PTPRJ Drives Clonal Selection in CEBPA-mutated AML

The data suggest that PTPRJ contributes to the mechanism of leukaemogenesis in CEBPA mutant AML by driving the selective pressure from each mutation to develop the other.

Alexandra Lubin, C. Hockings, Yvette Hoade et al. · 0 citations

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