Author

Esther Wolf

2 papers indexed here

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Open access Sep 2026

Chemically induced USP21-KLHL12 association recruits USP21 to COPII assembly

Ubiquitin-specific protease 21 (USP21) is a deubiquitinase implicated in various biological processes and disease states, including cancer. To better understand USP21 protein interaction networks, we used biotin identification proximity labeling, and uncovered USP21 interactions with the cytoskeleton, endosomal, and tr...

Victoria Vu, Michael Kanaris, Esther Wolf et al. · bioRxiv · 0 citations

Open access Jul 2026

Site-Specific Hydrogen–Deuterium Exchange Mass Spectrometry for Deep Explorations of Dynamic Shifts in Protein–Drug Interactions

Hydrogen–Deuterium eXchange Mass Spectrometry (HDX-MS) is a dynamics-sensitive structural method that has rapidly achieved widespread adoption in the biopharmaceuticals industry, owing to its ability to quickly identify binding sites and to provide a molecular mechanism of action for drug candidates. However, a central...

Joseph Anacleto, Esther Wolf, S. Ackloo et al. · Journal of the American Chem... · 1 citation