Author

Ethan P. Cisneros

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Open access Aug 2026

Surface chemistry governs sex-dependent responses to PEG and zwitterionic siRNA nanocarriers in primary macrophages

It is demonstrated that uptake alone does not predict functional efficacy and the importance of sex-informed evaluation when developing nanomedicines is highlighted.

Olivia L. Lanier, Brinkley A. Morse, Ethan P. Cisneros et al. · Science Advances · 1 citation

Review Open access Sep 2026

Chemical and Biological Determinants of PEG-Lipid Shedding From Therapeutic Nanoparticles.

Key factors that link PEG-lipid composition and nanoparticle architecture to desorption kinetics and biological outcomes are identified and provide guidance for the design of PEGylated nanomaterials with improved control over interfacial stability, immune recognition, and functional performance.

Ethan P. Cisneros, Aadya S. Wijesekera, Lisa R. Volpatti · Small · 0 citations