Author

Eun-A Ko

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Review Open access Sep 2026

Pathophysiological role of platelet-derived growth factors in chronic liver disease.

Platelet-derived growth factor (PDGF) and its receptor (PDGFR) signaling serves as a central driver of hepatic stellate cell (HSC) activation and extracellular matrix deposition in chronic liver diseases. Upon ligand binding, PDGFR undergoes dimerization and autophosphorylation, initiating key intracellular signaling p...

Eun-A Ko, Sung-Cherl Jung, E. Baek · Korean Journal of Physiology... · 0 citations

Review Open access Sep 2026

Platelet-Derived Growth Factor Receptor Alpha in Male Reproductive Health and Oxidative Stress: Stromal Homeostasis, Injury, and Research Perspectives

Oxidative stress is a well-recognized contributor to male reproductive dysfunction, yet discussion of this mechanism has focused almost exclusively on sperm damage. This focus overlooks the somatic and stromal networks that support testicular development, steroidogenesis, tissue architecture, and erectile function. Pla...

Eun-A Ko, J. Hwa, Dawon Kang · Antioxidants · 0 citations