Evan P. Cirves

Recruitment and local granulopoiesis of human hematopoietic stem/progenitor cells in a skin-on-a-chip.

Extramedullary hematopoiesis is increasingly recognized as an important mechanism by which peripheral tissues augment immune responses during inflammation and infection. However, the mechanisms governing recruitment, retention, and local differentiation of circulating hematopoietic stem and progenitor cells (HSPCs) wit...