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Evangelia Nathanail

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#diffusion models Open access Sep 2026

Integrative structural modelling reveals the human Mic60-Mic19 subcomplex as a diffusion barrier in mitochondria

Mitochondrial crista junctions (CJs) operate as regulated gateways into the cristae microenvironment, whose protein, metabolite, and ion compositions are finely tuned for mitochondrial function. The Mic60-Mic19 complex of the mitochondrial contact site and cristae organizing system (MICOS) complex was suggested to span...

Evangelia Nathanail, Edoardo Rolando, Max Ruwolt et al. · Nature Communications · 0 citations

Open access Jul 2026

Prediction-Guided Design of a More Developable FGF21 Construct

For structural-biology and protein-production pipelines, the hardest part of a difficult protein is not the biology — it is obtaining a well-behaved sample for functional studies. Programs routinely stall at construct design, expression, and purification: deciding where to truncate, which tags to use, how to express, a...

Çağlar Bozkurt, Evangelia Nathanail, Aniruddh Goteti · bioRxiv · 0 citations